ABSTRACT
Disabilities of upper extremities, as a sequela of stroke, often result in permanent functional complications which have received less attention in comparison to lower limb disabilities. Magnetic stimulation is a new therapeutic method which is used for induction of currents in the brain. The aim of this study was to compare the effect of magnetic stimulation on the wrist and elbow joints movements and grip force with that of routine rehabilitation. 12 hemiplegic patients were assigned to two groups. Patients in group I, received routine rehabilitation with placebo magnetic stimulation, and patients in group II, received magnetic stimulation with routine rehabilitation for 10 session, 3 times a week. Pre and post treatment evaluations were performed by use of Barthel index, Fugl-Meyer Motor Impairment Scale and dynamometer. In group I, Barthel and Fugl-Meyer indexes showed significant improvement, but no significant improvement noted in the rate of grip force. Group II, showed significant improvement in Barthel and Fugl-Meyer indexes and rate of grip force. When conventional treatment is not effective, rTMS can improve force and function of hand muscles in chronic hemiplegic patients
ABSTRACT
Oral mucositis frequently occurs in patients undergoing cancer chemotherapy. It is hypothesized that Oral Cooling with ice chips or cubes cause local vasoconstriction thus cause less exposure to agents and then mucositis development. In this study, this theory was examined on 14 patients in 3 consecutive cycles in which stomatitis developed in the 1 st cycle of treatment. The purpose of the present study was to evaluate the Ice-Therapy [mouth-cooling] in prevention or decreasing symptoms of chemotherapeutic-related stomatitis. Date was obtained on a total of 100 out-patients initiating chemotherapy regimens. The patients reported different rates of stomatitis received ice cubes in their 2nd cycle of treatment during the drug infusion and a few minutes after it. In the next cycle, the same patients were evaluated without mouth cooling. The severity of mucositis were measured based on the patient's judgment and scaled on WHO grading system in the 7th and 10th days. Statistically, comparison of severity rates of mucositis between 3 consecutive cycles were performed by mean, p value, GAMMA coefficient and Friedman test. Statistical approach of data between 3 cycles determined that severity rates of mucositis have been decreased significantly between 1st and 2nd cycles[p<0.01, gamma coefficient: 65%] But this relationship has not been obtained in comparison between 2nd and 3rd cycles so it has been speculated that Oral Cooling has no useful effect on the prevention of chemotherapy-induced mucositis. Oral Cooling has no evidence of benefit in improvement or decreasing of the chemotherapy induced lesions
Subject(s)
Humans , Hypothermia , Mucositis/therapy , Drug Therapy/adverse effects , Stomatitis/therapyABSTRACT
Statement of Problem: Amalgam is the most widely used dental restorative material. However, because of continuous low-level release of Mercury from amalgam fillings, its safety has been questionable
Purpose: The aim of this study was the evaluation of concentration of Mercury in saliva before and after amalgam fillings and its relation with numbers and surfaces of amalgam fillings
Materials and Methods: In an analytic interventional study we surveyed concentration Mercury in saliva before and after amalgam fillings. Twenty-five Patients [9 male, 16 female] who referred to oral medicine department of Tehran university of medical science and Haj- Abdol- Vahab medical center who had no amalgam fillings were selected and the samples of saliva [5cc] was collected before fillings. After that all of posterior decayed teeth were filled in an appointment with amalgam and, 24 hours later, the second samples of saliva [5cc] was collected. The amount of saliva Mercury before and after filling was measured and its difference was analyzed by paired t- test
Results: In this study the mean of Mercury in saliva was 0.00896 microg/ml before and 0.16404 microg/ml after amalgam fillings. The mean of number of fillings was 1.96 and mean of size of surfaces was 76.43 mm2 and mean of consumption amalgam was 4.1 units
Conclusion: There was no significant correlation between age [P=0.677], sex, number of fillings [P=0.055], number of surface of filling [P=0.059] and size of surfaces of fillings [P=0.072], with Mercury levels in saliva after amalgam fillings. There was a significant relation between Mercury level of saliva after fillings and amalgam amount [P= 0.036]. Therefore amalgam may be designate a significant source for Mercury release in saliva. Since this is a preliminary study, it needs supplementary evaluations in saliva, blood and urine in different periods after amalgam fillings